The Pasteur was commanded by Captain Matthew O'Hara in 2269 when it was destroyed by a high-intensity particle beam. (TOS - Year Four comic: "Issue 6") Several successor vessels were named after this ship—two hospital ships, the M'Benga-class USS Pasteur and the Olympic-class USS Pasteur, as well as the Nebula-class USS Pasteur. (FASA RPG module: Star Trek: The Next Generation Officer's Manual; ST website: The Path to 2409; TNG episode, novelization & comic adaptation: All Good Things...; ST video game: Armada II)