Bitores Mendez will be formally fought at the Slaughterhouse in Chapter 2-3 of the main game. As the player approaches the barn a cutscene will play where Leon enters it himself and the chief ambushes him. The player must dodge his attack via a quick time event or they will get a game over scene. Being successful initiates the fight after the scene. Ashley will not be present during the fight, as she was left outside.