The Riot of the Blood is a circumstance that affects individuals with partial Orochi ancestry in their bloodlines. This condition happens when outer influences or an event makes the Orochi blood in a person resist their normal blood. In most common instances, those afflicted go completely berserk. Those with full Orochi blood, including those who are already insane as Ryuji Yamazaki are not affected by this uncontrollable state. Orochi and his followers can directly trigger this within themselves and others.