They are the prime enemies of Sniffles. An episode where they appear first shows Sniffles as the antagonist when he tries to eat them. The ants are later shown to be the true villains when they torture him in extremely gruesome ways that almost always lead to his death. The most noteworthy example is in the episode Tongue In Cheek, in which they take control of his body and force him to do things that cause him agonizing pain, such as taking bites out of a razor-bladed apple, putting his tongue in a paper shredder, and nailing his tail to the ground; eventually bringing him to extreme tears.