Kabuto claims that this technique is the reason that Orochimaru values him so highly: he can keep using test subjects for much longer than is normally feasible. The technique will continue to heal damage until the user runs out of chakra, leaving the possibility that the damage will not be completely mended when the technique ends. Kintaro Uchiha uses this in combination with his Passive Regeneration Ability, giving him an extremely high level of endurance and constitution.