Francesco II Sforza (February 4, 1495 – October 24, 1535), also known as Francesco Maria Sforza, was Duke of Milan from 1521 until his death. He was the second son of Ludovico Sforza and Beatrice d'Este. When Ludovico was ousted from Milan in the course of the Italian Wars, he brought Francesco with him to the court of the Emperor Maximilian I, who had married a Sforza, Francesco's cousin Bianca Maria. Francesco was assigned to an ecclesiastical career. His father was imprisoned in Loches by Louis XII, and died in 1508, but when Charles V re-conquered Milan from the French in 1521, Francesco was appointed its duke, the last of the family to hold that title. His sovereignty, however, remained circumscribed by the military occupation of Milan by Spanish troops.