Guadalupe Joseph Arenas (born December 12, 1925 in Cedar Rapids, Iowa), also known as "Lupe Joe" Arenas and "Little Joe" Arenas, is a former American football player. He was a halfback and defensive back for the San Francisco 49ers from the 1951 to 1957. He was best known as a kickoff and punt returner. His 4,572 career kick and punt return yards was the best in NFL history at the time of his retirement, and his career average of 27.3 yards per kick return remains ninth best in NFL history. Arenas was, along with Tom Fears and Eddie Saenz, among the first Mexican-American players to achieve significant success in the sport of American football.