During a full moon night, Numbuh 4 and 3 are outside of the Sector V Treehouse overlooking the stars. While Numbuh 4 tries to hint at such a nice night, Numbuh 3 is in discomfort due to drinking an experimental remedy for Numbuh 74.239's experiment in isolating the cootie gene. Numbuh 4 waves her pain due to a stomach ache and tries to reveal his true feelings for her nervously. Numbuh 3 tries to dissuade him, due to her stomach acting up even more and she doubles in pain as Numbuh 4 continues his speech, telling her not to interrupt since they aren't alone enough much these days.