The Harmony Skirmish was a small engagement of the American Civil War between Confederate forces under Colonel John Mosby and Union forces under Colonel Marcus Reno on March 21, 1865 near the village of Harmony (present day Hamilton) in Loudoun County, Virginia. A union raiding party, that was sent into Loudoun County to eliminate Confederate partisans, was ambushed by Mosby's Rangers near the village of Harmony. After inflicting light casualties on the Federals, the Rangers were unable to drive off the numerically superior and better equipped force and were compelled to withdrawal. The skirmish, which was the last major action of the war within Loudoun, was tactically inconclusive.