Galaxy Zekbran was a stellar region of the galaxy's Alpha or Beta Quadrants. It had at least one habitable planet. In 2267, the USS Enterprise was exploring the so-called galaxy around stardate 31:09.5 when a mysterious force damaged one of its engines and burned out the replacement parts needed to repair it, forcing the crew to obtain zutotanium from the planet to make more. (TOS comic: "The Youth Trap")