He married Anne of Brandenburg in 1502 and had two children: * King Christian III of Denmark (1503 - 1561) * Duchess Dorothea of Prussia (1504 - 1577) He then remarried in 1518 to Sophie of Pomerania and had another three children: * Duke John of Holstein (1524 - 1581) * Prince Adolf of Denmark (1526 - 1526) * Prince Dietrich of Denmark (1532 - 1556)