When Jake Muller and Sherry Birkin escaped the Neo Umbrella medical facility, they saw themselves in the middle of the bioterror attack in China, a helicoper and many J'avos on motorcycles kept following them, after avoiding the helicopeter's attack, they reach the Poisawan Courtyard but just to be cornered by Neo-Umbrella's troops. Chris Redfield and Piers Nivans arrive at the scene and recognize Jake and Sherry who were who were missing for six months, they decide to aid the pair. But later Chris decides to leave them on their own to continue to hunt down Ada Wong.