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Korean medicine originated in ancient times. In Samguk Yusa·Gojoseon (삼국유사·고조선), where the founding myth of Korea is recorded, there is a story of a tiger and a bear who wanted to reincarnate in human form and who ate wormwood and garlic. In Jewang Ungi (제왕운기), which was written around the time of Samguk Yusa, wormwood and garlic are described as 'eatable medicine', showing that, even in times when incantatory medicine was the mainstream, medicinal herbs were given as curatives in Korea. Moreover, the fact that wormwood and garlic are not found in ancient Chinese herbology shows that traditional Korean medicine developed unique practices.

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