The USS Constitution (NCC-1700-B) was an explorer starship of the Galaxy-class built by the Federation Starfleet. (Trekmania) The Constitution, under command of Jules van Osterlich, was one of two Federation starships in 2364 to respond to reports of a deadly prion-based infection (which was years later found to be engineered by Thallonian General Gerrid Thul). (TNG novel: Infection) This ship's registry was not in any of its novel appearances, but was derived by the fan fiction reference Trekmania.