Serena Johnson was one of the suspects during the murder investigations of Jerry Bigwall in Blood and Glory (Case #42 of Grimsborough), Abigail Price in Good Girls Don't Die (Case #48 of Grimsborough), and Adam Bentley in It All Ends Here (Case #51 of Grimsborough). During the murder investigation of Delsin Peota in There Will Be Blood (Case #56 of Grimsborough), Serena was arrested for her involvement in the Crimson Order's illicit activities and for ordering the hit on Adam Bentley.