Pre-Series Five years before the start of the series, House had an infarction in his leg and was suffering from muscle death. After House refused amputation, his girlfriend Stacy Warner gave consent to have the muscle surgically removed while House was in a drug-induced coma, saving his life. 3X15 Half-Wit House convinced Cuddy, Wilson, and his team that he had a terminal brain cancer and only had a year to live. It is revealed that House faked the cancer in order to enter a drug trial where a chip would be installed in the pleasure center of his brain.