Cuddles is owned by science teacher Mr. Murphy, who punishes Evan Ross to clean Cuddles' cage, whom Evan dislikes. To get back at Mr. Murphy for Evan, Andy feeds Cuddles some Monster Blood, but after awhile, he grows to an enormous size, and starts rampaging through the school. Evan eats some Monster Blood himself so that he can grow to Cuddles' size and do battle with him.