Camp Joe Holt was a Union base during the American Civil War in Jeffersonville, Indiana, across the Ohio River from Louisville, Kentucky on land that is now part of Clarksville, Indiana, near the Big Eddy. It was a major staging area for troops in the Western Theatre of the War, in preparation for invading the Confederate States of America. Its establishment was the first major step performed by Kentucky Unionists to keep Kentucky from seceding to the Confederacy. The Interpretive Center for the Falls of the Ohio State Park was built where Camp Joe Holt existed.