HMS Antelope was a 50-gun fourth rate ship of the line of the Royal Navy, launched at Rotherhithe on 13 March 1703. She was rebuilt once during her career, and served in the Seven Years' War and the American Revolutionary War. Orders were issued on 9 January 1738 for Antelope to be taken to pieces and rebuilt according to the 1733 proposals of the 1719 Establishment at Woolwich, from where she was relaunched on 27 January 1741.