USS Reliant (NCC-44686) was an Ambassador-class heavy cruiser in Starfleet service during the mid 24th century. (Kennedy Shipyards: Starfleet Vessel Miranda Class Starship USS Reliant NCC-1864: General Blueprints and Specifications) The Reliant was commanded by Captain Katanna Lex in the 2350s and 2360s, during the Cardassian War and up to its destruction at the Battle of Wolf 359. (Star Trek: The Adventures of Argus)