Later analysis indicated Prozostrodon was more closely related to the mammals than to the Thrinaxodon species, and it was given its own genus. Cladistic anaysis indicates its closest relatives gave rise to the first mammaliaforms and therefore to the crown group mammals. Prozostrodon was found in the Geopark of Paleorrota, Santa Maria Formation, Brazil and is deposited in the paleontology museum of the UFRGS.