Joe Bob Isbell (born July 7, 1940 in Gorman, Texas) is a former American football offensive lineman in the National Football League for the Dallas Cowboys and Cleveland Browns. He played college football at the University of Houston and was selected in the twentieth round of the 1962 AFL Draft by the Houston Oilers. Joseph Robert (Joe Bob) Isbell was born to Earl D. and Beulah Alexander Isbell. His father was only a fifth cousin of professional ballplayers and fellow Texans Cecil Isbell, Larry Isbell, and Cody Isbell.