The Mainframe Rebellion is a small organization created by Dot Matrix and Mouse during the last part of the Viral Wars to combat Megabyte and his viral army when he took control of Mainframe, renaming it Megaframe. The rebellion was made up of the remains of the CPU defense force. They had no defense vehicles, operating as a gorilla ground force. The headquarters was set up in a small warehouse located in the lower levels of the city. Hack and Slash would often patrol the city to provide reconnaissance for Dot and Mouse.