A Pox on Our House is a 7th season episode of House which first aired on November 15, 2010. It was directed by Tucker Gates. A girl is admitted with symptoms that appear to indicate smallpox, and the CDC institutes a lockdown. However, House is skeptical. When the doctor in charge forbids House's team from diagnosing, Masters believes he has an ulterior motive. House, convinced he is right, he breaks quarantine, seemingly at the risk of his own life. Meanwhile, Wilson and Sam re-examine their relationship while treating a young chemotherapy patient. House worries that Cuddy has uncovered his deception with a previous patient and the effect it will have on his relationship.