John Cole's Book Shop (originally John Cole's Book and Craft Shop) was a bookstore in La Jolla, San Diego, California. It was founded in 1946 by John (d. 1959) and Barbara Cole (d. 2004) on Ivanhoe Avenue, and moved in 1966 to the Wisteria Cottage at 780 Prospect Street. The cottage had housed Ellen Browning Scripps' half-sister Virginia, and La Jolla Country Day School, prior to becoming the location of John Cole's Book Shop. Theodor Seuss Geisel, better known as Dr. Seuss, lived nearby and regularly signed books for the shop.