The film follows the events that unfold at Tromaville High School in New Jersey, which is conveniently located next to a nuclear power plant. The gang of the school, called "The Cretins", deal drugs among the students. They pick leaves from a radioactive marijuana plant located in the yard of the nuclear plant and sell it to Eddie for $10. He smokes it at a party with his friends Warren and Chrissy. That night, they both have hallucinations. Chrissy discovers that she is pregnant, and spits a little monster into a nearby toilet. The creature travels through the water pipes and lands in a barrel filled with radioactive waste, and mutates into a bigger creature. Meanwhile, Warren has super strength and kills two of the Cretins. The rebel gang takes over the school and start destroying it, an