Isokaze (磯風?, "Wind on the Beach") was a Kagero-class destroyer of the Imperial Japanese Navy. It is the second ship to carry the name after the lead ship from Isokaze-class destroyer. On 7 April 1945, Isokaze escorted the battleship Yamato from the Inland Sea on her Operation Ten-Go attack on the Allied forces on Okinawa. She was struck by aircraft of Task Force 58 and scuttled by Yukikaze with gunfire 150 miles (280 km) southwest of Nagasaki (30.46°N 128.92°E). Of those on board, 20 were killed and rest were rescued by other ships. Yamato's other escorts, including Hamakaze, Asashimo and Yamato herself, were sunk afterwards, Asashimo losing all hands during the encounter.