The USS Centaur (NCC-42043) was a Federation Centaur-type starship operated by Starfleet. In 2374, the Centaur was under the command of Captain Charlie Reynolds. In that year, the Centaur mistakenly attacked a Jem'Hadar attack ship being commanded by Captain Benjamin Sisko for a covert mission. The Centaur pursued the attack ship into Dominion territory before being chased off by additional Jem'Hadar ships. (DS9: "A Time to Stand") The Centaur was also part of the fleet that carried out Operation Return a few weeks later. (DS9: "Sacrifice of Angels")