The 2010 East–West Shrine Game was the 85th staging of the all-star college football exhibition game featuring NCAA Division I Football Bowl Subdivision players. The game featured over 100 players from the 2009 college football season, and prospects for the 2010 Draft of the professional National Football League (NFL), as well as for the United Football League's inaugural draft. In the week prior to the game, scouts from all 32 NFL teams attended. The proceeds from the East-West Shrine Game benefit Shriners Hospitals for Children.