The family tree of the Egyptian Nineteenth Dynasty is the usual mixture of conjecture and interpretation. The family history starts with the appointment of Ramesses I as the successor to Horemheb, the last king of the Eighteenth Dynasty who had no heirs (although it is speculated that Isetnofret, a wife of Ramesses II, was related to him). From Ramesses's line came perhaps the greatest king of the New Kingdom, Ramesses II. He ruled for nearly 66 years and had many children, many of them pre-deceased him and were buried in tomb KV5 in the Valley of the Kings, near Thebes.