John Hartwell Cocke II (or Jr.) (September 19, 1780 – June 24, 1866) was an American military officer, planter and businessman. During the War of 1812, Cocke was a brigadier general of the Virginia militia. After his military service, he invested in the James River and Kanawha Company and helped Thomas Jefferson establish the University of Virginia. The family estate that Cocke built at Bremo Plantation is now a National Historic Landmark.