USS Mary Alice (SP-397) was a United States Navy patrol vessel commissioned in 1917 and sunk in 1918. Mary Alice was built as the fast, private steam yacht Bernice in 1897 in Brooklyn, New York. She was renamed Oneta in 1907 and Mary Alice in 1910. On 10 August 1917, the U.S. Navy purchased Mary Alice from William J. Connors of Buffalo, New York, for use as a section patrol vessel during World War I. She was commissioned as USS Mary Alice (SP-397) the same day with Lieutenant, junior grade, Grant Campbell, USNRF, in command.