Despite stating a lack of interest in science fiction (AUDIO: The Fearless: Part 1, extra interview), in recent years O'Brien has worked on a number of Doctor Who-related audio plays for Big Finish Productions, initially playing a new character for the Dalek Empire IV miniseries, as well as for the audio story Year of the Pig, then reprising the role of Vicki for the Companion Chronicles. She has also participated in DVD commentaries and interviews for BBC Video releases of stories from her era.