Picking up directly where Issue 1 left off, after Hirsch's close encounter with two infected, Selena, Clint and the group immediately flee for a nearby abandoned hotel as another infected arrives and gives pursuit. The group just escape into the hotel from the infected, with Selena narrowly saving Randall's life in the process, then set about getting to Sumburgh to catch Clint's friend's boat to the mainland in time. Selena and a reluctant Derrick head out into the hotel's car park to hotwire a van for the group to reach Sumburgh in, while the others stay behind in the hotel to find weapons.