Aliens vs. Predators: Evolution is a science fiction-horror film starring Vanessa Lee Evigan, Kerr Smith, Shawn Ashmore, Mason Cook, Jesse Metcalfe, Chris Evans, Mary Elizabeth Winstead, Addy Miller, Ben Foster, A.J. Cook, Chris Zylka, Katharine McPhee, Rutina Wesley, Abigail Breslin, Dustin Milligan, Chris Klein, Topher Grace, James Franco, Alyson Hannigan, Neil Patrick Harris, Josh Duhamel, Megan Fox, Emanuelle Chriqui, Eric Christian Olsen, Alyssa Milano, Arlen Escarpreta and Nick Stahl