Monergism describes the position in Christian theology of those who believe that God through the Holy Spirit works to effectually bring about the salvation of individuals through spiritual regeneration without cooperation from the individual. Monergism is most often associated with Calvinism (e.g., Presbyterians and Dutch Reformed) and its doctrine of irresistible grace and in particular with historic doctrinal differences between Calvinism on the one hand and Arminianism on the other.