The 46th Virginia Volunteer Infantry Regiment was an infantry regiment raised in Virginia for service in the Confederate States Army during the American Civil War. It fought mostly in Virginia and the Carolinas. 46th Infantry Regiment (also called 1st or 2nd Regiment, Wise Legion) was organized in August, 1861. This unit contained 401 effectives during the Seven Days' Battles and surrendered 15 officers and 116 men on April 9, 1865.