Colonel William Graham (1742–1835) was militia and political leader from North Carolina during the American Revolution. Graham was born in Augusta County, Virginia, the son of Archibald Graham of Scotland. The younger Graham moved to the Province of North Carolina several years before the American Revolutionary War. There he was one of forty signers of the Tryon Resolves. In 1776, he served as a delegate from Lincoln County to the North Carolina Provincial Congress. As a colonel of militia, he served under General Griffith Rutherford in the successful expedition against the Cherokees in 1776.