When it comes to long running Japanese manga sagas, which later become animes, one of two things happen. The anime contains exactly the same content as the manga (as is the case with contemporary examples like Gunslinger Girl), down to precisely replicating scenes, or to stimulate new interest or a different age group, the content varies. Both Appleseed and GITS are like this, with each series differing significantly from the mangas that inspired them. So complicated are the differences between Appleseed as a book and motion picture, another chart is needed, just to summarize a few.