.450 Nitro Express designed for the purpose of hunting large game such as elephant. This cartridge is used almost exclusively in single shot and double express rifles for hunting at the Tropics or hot climates in general and is a cartridge associated with the Golden Age of African safaris and Indian shikars. A prominent user was Frederick Courteney Selous, whom using this cartridge in Farquharson rifle was the inspiration for the character of Allan Quatermain.