A haloalkane also known as alkyl halogenide, halogenalkane or halogenoalkane, and alkyl halide is a chemical compound derived from an alkane by substituting one or more hydrogen atoms with halogen atoms. Substitution with fluorine, chlorine, bromine and iodine results in fluoroalkanes, chloroalkanes, bromoalkanes and iodoalkanes, respectively. Mixed compounds are also possible, the best-known examples being the chlorofluorocarbons (CFCs) which are mainly responsible for ozone depletion. Haloalkanes are used in semiconductor device fabrication, as refrigerants, foam blowing agents, solvents, aerosol spray propellants, fire extinguishing agents, and chemical reagents.