During the Third Shinobi World War, Misake commanded Tobikakurenai's Sensory Division , transmitting information and tactics for all platoons on the battlefield. Years later, when he was already married and had assumed the family business assuming the position of Hisajima's Perfume Shop owner, Misake was surprised when his only daughter Miyuki suffered an accident during a mission at the Land of Wood and from that mission, can not more work as shinobi. During Miyuki's postoperative, Misake gave full support to his daughter trying to get better her emotional. Trying to ease his daughter's pain, he gave her a job in the family store.