The Second Peace of Thorn of 1466 (; ) was a peace treaty signed in the Hanseatic city of Thorn (Toruń) on 19 October 1466 between the Polish king Casimir IV Jagiellon on one side, and the Teutonic Knights on the other. The treaty concluded the Thirteen Years' War (1454–1466) which had begun in February 1454 with the revolt of the Prussian Confederation, led by the cities of Danzig (Gdańsk), Elbing (Elbląg), Kulm (Chełmno) and Thorn, and the Prussian gentry against the rule of the Teutonic Knights in the Monastic State.