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Manuel Uribe (June 11, 1965-May 26, 2014) was a man from Monterrey, Nuevo León, Mexico, notable for suffering from morbid obesity to one of the greatest extents known in recorded history. After reaching a peak weight of around 597 kg (1,316 lb) and having been unable to leave his bed since 2001, Uribe lost approximately 181 kg (399 lb) (one third of his body weight) with the help of doctors and nutritionists, and by following the Zone diet. Uribe drew worldwide attention when he appeared on the Televisa television network in January 2006, but turned down offers for gastric bypass surgery in Italy.

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