Lisa Guthrie is K.C. Guthrie's mother and a recovering drug addict. She gave birth to K.C. when she was a teenager, but K.C. was taken away from her while she was abusing drugs, specifically crack. When this happened, K.C. was put into a group home, as both Lisa and his father Kevin Guthrie were in prison. Recently, Lisa got out of jail and tried to win custody of K.C. again; something he originally fought, but eventually accepted. She offered to help Jenna with her pregnancy, but respected K.C. and Jenna's decision to give Tyson up for adoption. She has also respected K.C.'s choice to be in the baby's life. She recently left with her son to get away from her ex-husband. She was portrayed by Robin Brûlé.