Lockpicking is an Ability in Divinity: Original Sin under the Nasty Deeds section, made available to the main characters and party members, allowing them to bypass locked doors and containers to gain access to areas or misc loot. Although simple locks can be opened using the Lockpick item with no investment into this Ability, more complex locks will require higher levels to successfully be opened. Without sufficient level, you will be given a message prompt stating the lock is too high level.