Ware is perhaps best known for her part as Rosie in Cocoon (1985, featuring Clint Howard, cinematography by Don Peterman and music by James Horner). She had a role in 2010 (1984) as Jessie Bowman, Astronaut David Bowman's mother. The film featured make-ups by Michael Westmore. She also guested in TV shows such as The Golden Girls and ER.