Following the death of Konrad Curze at the hands of the female Callidus Assassin known as M'Shen after the death of Horus, Talos disobeyed his Primarch's last order and was the first to hunt the Imperial Assassin in the name of righteous vengeance. This is how he earned his sobriquet the "Soul Hunter" as had been prophesied by his Primarch before his death: