In the 1524 Siege of Edo, also known as the Battle of Takanawahara, the Hōjō, led by Hōjō Ujitsuna, besieged Edo castle, which was held by Uesugi Tomooki. Though Edo has since become the Japanese metropolis of Tokyo, it was then a more or less insignificant fishing village in the Kantō region. This battle would mark the beginning of a seventeen-year struggle between the Hōjō and Uesugi clans for dominance of the Kantō.