The Proceedings of the National Academy of Sciences of the United States of America, usually referred to as PNAS, is the official journal of the United States National Academy of Sciences. PNAS is an important scientific journal that printed its first issue in 1915 and continues to publish highly cited research reports, commentaries, reviews, perspectives, feature articles, colloquium papers, profiles, letters to the editor, and actions of the Academy. Coverage in PNAS broadly spans the biological, physical, and social sciences. Although most of the papers published in the journal are in the biomedical sciences, PNAS recruits papers and publishes special features in the physical and social sciences and in mathematics. PNAS (abbreviated Proc Natl Acad Sci USA for referencing and indexing pu